Salivary Gland Transcriptomes and Proteomes of Phlebotomus tobbi and Phlebotomus sergenti, Vectors of Leishmaniasis
نویسندگان
چکیده
منابع مشابه
Salivary Gland Transcriptomes and Proteomes of Phlebotomus tobbi and Phlebotomus sergenti, Vectors of Leishmaniasis
BACKGROUND Phlebotomus tobbi is a vector of Leishmania infantum, and P. sergenti is a vector of Leishmania tropica. Le. infantum and Le. tropica typically cause visceral or cutaneous leishmaniasis, respectively, but Le. infantum strains transmitted by P. tobbi can cause cutaneous disease. To better understand the components and possible implications of sand fly saliva in leishmaniasis, the tran...
متن کاملComparative Analysis of Salivary Gland Transcriptomes of Phlebotomus orientalis Sand Flies from Endemic and Non-endemic Foci of Visceral Leishmaniasis
BACKGROUND In East Africa, Phlebotomus orientalis serves as the main vector of Leishmania donovani, the causative agent of visceral leishmaniasis (VL). Phlebotomus orientalis is present at two distant localities in Ethiopia; Addis Zemen where VL is endemic and Melka Werer where transmission of VL does not occur. To find out whether the difference in epidemiology of VL is due to distant composit...
متن کاملRearing and Biology of Phlebotomus sergenti, the Main Vector of Anthroponotic Cutaneous Leishmaniasis in Iran
Background Establishment of sand flies laboratory colonies is essential to understand various biological aspects of Phlebotominae sand flies. The aims of the current study were to establish the colony of Phlebotomus sergenti Parrot (1917), the main vector of anthroponotic cutaneous leishmaniasis in old world, and to study biological parameters of this species. Methods The sand flies were rear...
متن کاملSalivary gland homogenates of the sand fly Phlebotomus
insects and ticks. Perhaps for this reason a variety of salivary anti-hemostatic compounds are found in this diverse group of arthropods. Many different salivary anti-clotting and antiplatelet agents and vasodilators have been described. Salivary vasodilators range from inorganic nitric oxide to prostaglandins, various different peptides and enzymes that destroy norepinephrine. Several anti-clo...
متن کاملIndividual variability of salivary gland proteins in three Phlebotomus species.
Pooled salivary gland samples are frequently used to ensure the sufficient amount of material for the experiments; however, this could mask an individual variability. Thus, we compared salivary protein profiles in seven colonies of three Phlebotomus species: Phlebotomus sergenti, Phlebotomus perniciosus, and Phlebotomus papatasi. Surprisingly, the individual profiles differed significantly betw...
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ژورنال
عنوان ژورنال: PLoS Neglected Tropical Diseases
سال: 2012
ISSN: 1935-2735
DOI: 10.1371/journal.pntd.0001660